Are you just using macpack, or also mkbundle? I've tried fiddling with mkbundle off and on but the Mono.framework from the Mono site doesn't do the stuff with pkg-config that mkbundle expects, and I don't have the free time to pretend I'm on Linux and go hunting for dependencies.

I've been working on a C# game API for the last couple of months with the full expectation that I'll eventually convert my entire development over to .NET; if you want to contribute to it, it would probably give me the motivation to bring it up to par feature-wise with my C++ game API. Right now it's been kind of sitting on my hard drive waiting for some major revisions. I do a pass over it with MoMa as part of my build process, so it's Mono and MSCLI compatible.